Hisato Kawakami Selected Research

Melanoma (Melanoma, Malignant)

1/2021	Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts.
1/2016	Phase 1 study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced solid tumors.

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Hisato Kawakami Research Topics

Disease

61	Neoplasms (Cancer) 05/2024 - 05/2009
37	Stomach Neoplasms (Stomach Cancer) 05/2024 - 05/2012
29	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 04/2011
9	Esophageal Squamous Cell Carcinoma 05/2024 - 01/2019
9	Disease Progression 01/2024 - 01/2016
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2022 - 07/2014
7	Adenocarcinoma 08/2023 - 01/2020
7	Esophageal Neoplasms (Esophageal Cancer) 10/2022 - 08/2015
4	Microsatellite Instability 01/2023 - 07/2015
4	Breast Neoplasms (Breast Cancer) 02/2020 - 10/2014
3	Neutropenia 09/2023 - 10/2014
3	Neoplasm Metastasis (Metastasis) 10/2021 - 05/2012
3	Squamous Cell Carcinoma of Head and Neck 09/2019 - 12/2013
2	Colitis 03/2024 - 01/2022
2	Febrile Neutropenia 09/2023 - 12/2018
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2023 - 12/2020
2	Oropharyngeal Neoplasms 10/2021 - 01/2018
2	Melanoma (Melanoma, Malignant) 01/2021 - 01/2016
2	Pneumonia (Pneumonitis) 01/2020 - 01/2016
2	Deglutition Disorders (Dysphagia) 01/2019 - 10/2017
2	Diarrhea 12/2018 - 10/2014
2	Carcinoma (Carcinomatosis) 10/2017 - 04/2015
2	Colonic Neoplasms (Colon Cancer) 12/2016 - 09/2015
2	Chromosomal Instability (Chromosome Stability) 12/2015 - 07/2015
1	Ulcerative Colitis 03/2024
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2024
1	Vascular Remodeling 01/2024
1	Testicular Neoplasms (Testicular Cancer) 01/2023

Drug/Important Bio-Agent (IBA)

19	NivolumabIBA 05/2024 - 01/2017
13	Biomarkers (Surrogate Marker)IBA 05/2024 - 05/2016
12	Docetaxel (Taxotere)FDA Link 01/2024 - 08/2015
12	Cisplatin (Platino)FDA LinkGeneric 11/2023 - 05/2012
9	Fluorouracil (Carac)FDA LinkGeneric 01/2024 - 08/2015
8	PlatinumIBA 04/2024 - 10/2017
8	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2019
8	LigandsIBA 01/2023 - 12/2014
7	Capecitabine (Xeloda)FDA Link 11/2023 - 05/2012
7	Oxaliplatin (Eloxatin)FDA LinkGeneric 08/2022 - 01/2020
6	trastuzumab deruxtecanIBA 05/2024 - 12/2019
6	Bevacizumab (Avastin)FDA Link 01/2024 - 07/2020
6	trifluridine tipiracil drug combinationIBA 01/2024 - 12/2020
6	Irinotecan (Camptosar)FDA LinkGeneric 09/2023 - 01/2021
6	pembrolizumabIBA 09/2023 - 01/2016
6	Tyrosine Kinase InhibitorsIBA 01/2022 - 01/2013
5	ErbB Receptors (EGF Receptor)IBA 05/2024 - 01/2016
5	B7-H1 AntigenIBA 05/2024 - 01/2022
5	Cetuximab (Erbitux)FDA Link 12/2022 - 08/2011
5	Neuregulin-1 (Neuregulin 1)IBA 09/2019 - 12/2014
4	IpilimumabIBA 05/2024 - 02/2021
4	S-1 plus cisplatinIBA 11/2023 - 12/2018
4	human ERBB2 proteinIBA 01/2023 - 12/2019
4	Monoclonal AntibodiesIBA 01/2022 - 01/2016
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2021 - 09/2015
4	Trastuzumab (Herceptin)FDA Link 02/2020 - 12/2016
3	taxaneIBA 04/2024 - 10/2022
3	RamucirumabIBA 08/2023 - 12/2020
3	Paclitaxel (Taxol)FDA LinkGeneric 10/2021 - 10/2014
3	ParaffinIBA 01/2021 - 01/2013
3	Formaldehyde (Formol)FDA Link 01/2021 - 01/2013
3	Messenger RNA (mRNA)IBA 09/2019 - 07/2014
3	nedaplatinIBA 01/2019 - 12/2013
3	patritumabIBA 01/2019 - 12/2014
3	Small Interfering RNA (siRNA)IBA 01/2018 - 04/2015
2	SteroidsIBA 03/2024 - 01/2017
2	eribulin FDA Link 01/2024 - 01/2024
2	Cell-Free Nucleic AcidsIBA 01/2024 - 01/2023
2	Panitumumab (Vectibix)FDA Link 01/2023 - 01/2021
2	encorafenibIBA 12/2022 - 06/2021
2	binimetinibIBA 12/2022 - 06/2021
2	AntibodiesIBA 10/2022 - 07/2016
2	patritumab deruxtecanIBA 01/2022 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2019
2	cobimetinibIBA 01/2018 - 12/2016
2	Alanine Transaminase (SGPT)IBA 01/2017 - 01/2016
2	Calcibiotic Root Canal SealerIBA 12/2015 - 07/2015
1	Protein Isoforms (Isoforms)IBA 04/2024
1	Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA 04/2024
1	bemarituzumabIBA 04/2024
1	tyrosine receptor (receptor, tyrosine)IBA 04/2024
1	zolbetuximabIBA 04/2024
1	Phosphotransferases (Kinase)IBA 04/2024
1	AutoantibodiesIBA 03/2024
1	IntegrinsIBA 03/2024
1	Tumor Biomarkers (Tumor Markers)IBA 01/2024
1	S 1 (combination)IBA 09/2023
1	Bendamustine Hydrochloride FDA Link 01/2023
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2023
1	Trifluridine (Viroptic)FDA LinkGeneric 01/2023
1	AntigensIBA 01/2023

Therapy/Procedure

44	Therapeutics 04/2024 - 07/2014
34	Drug Therapy (Chemotherapy) 05/2024 - 04/2011
6	Adjuvant Chemotherapy 01/2023 - 07/2015
5	Combination Drug Therapy (Combination Chemotherapy) 03/2022 - 12/2019
5	Immunotherapy 01/2022 - 01/2019
4	Neoadjuvant Therapy 04/2023 - 12/2018
4	Gastrectomy 01/2023 - 01/2020
3	Aftercare (After-Treatment) 07/2019 - 10/2017
2	Lymph Node Excision (Lymph Node Dissection) 01/2023 - 07/2022
2	Radiotherapy 10/2021 - 01/2018
2	Precision Medicine 06/2021 - 01/2021